Compared to other wrinkles, pleats and creases can prove especially stubborn to iron out of pants. Whether they are the original pleats and creases or new, stubborn creases caused from sitting in a drawer or getting tangled up in the dryer, you can choose from several methods to remove them from your pants. Begin by washing and drying your pants according to their label instructions to loosen up the pleats or creases. Always set your iron to the fabric type of your pants and test each ironing method in an inconspicuous area of your pants to avoid ruining the fabric.

Place your pants on a clean ironing board. Fill a spray bottle with distilled water -- using distilled water will reduce the mineral buildup on your pants. Spray the water directly onto the pleat or crease you wish to remove from your pants. Iron your pants as usual, applying pressure to the iron as you smooth it slowly across the pleat or crease of your pants.

Spray some spray starch lightly onto your pants, concentrating it on the pleat or crease you wish to iron out. Slowly iron out your pants as usual on the ironing board. Make your own spray starch by mixing one tablespoon of cornstarch with two cups of water. To prevent flaking when you’re using spray starch, set your iron at a medium heat setting or below; avoid high heat.

Turn your pants inside-out. Rub a bar of soap on the inside of your pants, along the line of the pleat or crease. Turn your pants right side-out and iron them as usual on the ironing board.

Dampen a clean cloth with white vinegar. Rub this cloth on the pleat or crease of your pants, then iron them as usual. Wash and dry your pants to get rid of the vinegar smell, then iron them again. This extra wash may also aid you in getting the pleat or crease out.