How to Use Antioxidants With Benzoyl Peroxide

by Darin McGilvra ; Updated September 28, 2017

Benzoyl peroxide is a compound commonly used in creams or lotions that are used to prevent or control acne. According to, antioxidants are compounds used to neutralize the free radicals produced by oxidants, which are known to cause damage to skin cells. The most common antioxidants are Vitamin A, alpha-lipoic acid, Vitamin C and Vitamin E. Benzoyl peroxide is an oxidant--its oxidizing effect penetrates the pores and attacks the bacteria that cause acne. If an antioxidant is used at the same time as an oxidant such as benzoyl peroxide, they will neutralize each other and neither will work properly.

Clean your face with a face cleanser just before going to bed every night. Pat dry with a towel.

Apply the acne cream or lotion containing benzoyl peroxide to your face, following the instructions on the package. Allow the benzoyl peroxide to work overnight.

Clean your face with a face cleanser every morning. Pat your face dry with a towel.

Apply the face cream or lotion containing antioxidants to your face.


  • The concentration of benzoyl peroxide in any lotion or cream can be 2 percent to 10 percent in non-prescription products, as required by the U.S. Food and Drug Administration. The amount of benzoyl peroxide you should use depends on how much it irritates your skin and how much acne you have. In general, start with a lower concentration and increase as necessary.

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