Silicone sealant, or caulk, is commonly used to bond or hide joints in bathrooms, kitchens and other plumbing or tile fixtures. It is a highly effective adhesive that prevents leaks, water damage and rusting. Removing silicone sealant from your hands after a messy project may seem difficult, but a common household product can help. Nail polish removers that contain acetone are the safest solution to quickly remove silicone from skin.

Wash your hands with soap and warm water two to three times to soften the residue. Carefully peel off any loose pieces to ease the removal.

Prepare a ventilated area and dampen a cotton pad with nail polish remover. Make sure it contains acetone, which is the chemical that will dissolve the silicone.

Rub the nail polish remover onto the affected areas until the silicone begins to loosen. Roll off the residue with your fingers to help the process along.

Rinse your hands with warm water and dry it with a clean cloth once the sealant has been completely removed. Apply a moisturizer to the area, as acetone can be safely applied to the skin but does tend to cause dryness.