Knuckle wrinkles are not as prominent as those on your face or neck, but they can be embarrassing and cause self consciousness. There are plenty of methods for removing them including home methods and clinical methods. It is also important to know how to go about preventing knuckle wrinkles to begin with. Use one or a combination of methods based on your individual preference and the severity of your wrinkles.

Moisturize your hands regularly. According to the MayoClinic.com, moisturizers help mask lines and creases, promoting a smoother, more youthful appearance. Fortunately, you don't have to be concerned about clogged pores producing acne breakouts on your hands so be sure to moisturize throughout the day. Look for creams and lotions designed specifically for hands that contain heavy moisturizers like shea butter or vitamin E.

Visit your doctor and inquire about clinical procedures. According to an article in The New York Times, some of the best treatments are laser resurfacing and filler injections.These treatments are used on hands and any other area of skin that is subject to wrinkling. Lasers and fillers range in price starting at $5,000 for lasers and $3,000 on up for fillers as of October 2010. The effects of these treatments last from few months up to two years, and multiple treatments may be necessary for consistent results.

Ask a plastic surgeon if fat grafting is ideal for you. This procedure eliminates knuckle wrinkles and gives hands a smoother, more youthful appearance. Fat grafting does not require several treatments and the results can last up to 10 years. However, the procedure is expensive and costs upwards of $12,000 as of October 2010.

Practice prevention daily. In addition to genetics and the aging process, sun exposure and smoking are two of the biggest culprits for knuckle wrinkles. Wear an SPF lotion everyday and quit smoking if this is a habit. Also avoid exposure to secondhand smoke. Dryness can also cause your skin to wrinkle more easily so take precautions to protect your hands. Wear rubber gloves when washing dishes or using chemicals to clean your home. Wash your hands with mild cleansers and moisturize them afterward.