Is Glucosamine for Cellulite Safe and Effective?

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Glucosamine is a naturally produced compound that is found throughout your body, particularly in cartilage and joint fluids, called synovial fluid. Glucosamine not only supports joint health, it may also play a role in maintaining healthy skin. Glucosamine can be taken orally or applied to your skin topically for its health benefits. Talk to your doctor about glucosamine supplements before using them to make sure they are safe for you.


Cellulite is the puckered appearance of skin caused by fibrous bands that divide sections of fat cells in your subcutaneous fat stores just underneath the surface of your skin. According to the book "Cellulite Solution," glucosamine may be one of the most important supplements in a cellulite-treatment program because it is the building block of skin tissue and can repair damage to your skin caused by cellulite.


According to a 2006 study published in the "Journal of Cosmetic Dermatology," both topical and oral glucosamine supplements may promote skin health and other benefits. The researchers found that glucosamine compounds can accelerate wound healing, improve skin hydration and decrease the appearance of wrinkles. More research needs to be conducted on the effect of glucosamine specifically on cellulite reduction.


Gglucosamine is considered likely safe for adults when used within the recommended guidelines. One popular form of oral glucosamine, glucosamine sulfate, can cause some mild side effects including nausea, heartburn, diarrhea and constipation. Some glucosamine products are derived from the shells of certain shellfish, so if you have a shellfish allergy, you should use these products with caution. However, most shellfish allergies result from the meat and not the shell of shellfish, making an allergic reaction to glucosamine supplements very rare.


Talk with your physician before using any product containing glucosamine to make sure it is right for you. According to the book "Pharmacology for Health Professionals," oral glucosamine supplements are usually consumed in a dosage of 1,500 mg daily, but doses can vary depending on your age and specific condition. There is no recommended dosage for topical creams, but applying between 60 and 120 mg of topical glucosamine sulphite can increase glucosamine levels throughout your body.